Peate CROU Pharmaceutical Online

I. Substance Attributes Database

(Includes basic profiles of active and inactive substances)

	 



	  



	 



	1.化学物质索引数据库（Chemical Index Database） 



	





	http://www.drugfuture.com/chemdata/index.aspx 



	





	 



	This database is a chemical substance properties database containing extensive information on the properties of substances with pharmacological and biological activity.



	





	Search conditions support fuzzy queries, with the relationship between input conditions being logical AND. Chemical structural formulas are vector-format images that can be viewed with lossless scaling using the system's built-in image preview tool or any tool supporting this format.



	





	Search results include:



	





	① Index Information: Such as substance name, chemical structure diagram, Chemical Abstracts Service (CAS) registry number, CAS name, trade name, chemical structure, molecular formula, molecular weight, elemental composition, etc.;



	





	② References: Provide highly valuable literature from key journals, patents, and reviews covering physical and chemical properties, preparation methods, analytical methods, pharmacology and efficacy, clinical studies, etc.;



	





	③ Substance Properties: Include physicochemical data such as melting point, boiling point, flash point, solubility, polycrystalline state, spectral absorption characteristics, therapeutic classification, etc.



	





	 



	2、Inactive Ingredient Search for Approved Drug Products 



	





	http://www.drugfuture.com/fda/IIG_query.aspx 



	





	This database contains inactive ingredients used in FDA-approved drugs, specifically excipient information included in FDA-listed products. Data updates are synchronized with the FDA.

Search conditions support fuzzy queries, with each input condition linked by a logical AND relationship.

Search results include: inactive ingredient name, route of administration or dosage form, CAS registry number, USP/FDA Material Identification System unique identifier, and quantity of excipient used in the formulation. This database provides factual data on safe excipient usage levels for drug research and development professionals.  



	 



	3.Handbook of Pharmaceutical Excipients 



	





	http://www.drugfuture.com/excipients/index.html 



	





	This database is designed based on The Handbook of Pharmaceutical Excipients (6th Edition), a globally recognized authoritative and comprehensive reference work on pharmaceutical excipients compiled by experts in excipient manufacturing technology worldwide.

This handbook provides a systematic introduction to the listed excipient entries, accompanied by comprehensive and detailed references. It is rich in data, highly referenceable, and user-friendly:

① It compiles fundamental physical property data for excipients, including boiling point, bulk density and tapped density, compressibility, deliquescence, flowability, melting point, moisture content, particle size distribution, rheology, specific surface area, and solubility. Additionally, scanning electron microscope (SEM) images are provided for many excipients.

② Includes an index searchable by chemical name, generic name, and trade name. Most entries feature a “Similar Substances” section, aiding formulation developers in creating new dosage forms.

③ Organized systematically with each entry divided into 22 sections for easy reference. Similar substances are discussed together for clear structure.

This handbook serves as an excellent reference tool for pharmaceutical research and production technicians, while also providing valuable guidance for professionals engaged in cosmetics and food research and manufacturing.

4. Chemical Toxicity Database

http://www.drugfuture.com/toxic/index.html

This database provides pharmaceutical developers with extensive toxicological and chemical safety information on active substances. It contains toxicological data for approximately 150,000 compounds (including numerous chemical drugs), such as acute toxicity, chronic toxicity, genotoxicity, carcinogenicity, reproductive toxicity, and irritation data, along with cited sources. Multiple search methods are available, including CAS Registry Number, English name, RTECS Number, chemical name, trade name, and development code.  



	





	II. Chemical Synthesis Database 



	  



	 



	1. Drug Synthesis Routes Database

http://www.drugfuture.com/synth/synth_query.asp

Database Description: This database is now fully constructed, providing access to all synthetic route literature, structural formulas, and synthetic route diagrams.

It offers information on the synthesis of nearly 7,000 marketed or investigational drugs, including drug names, structural formulas, chemical names, CAS registry numbers, molecular formulas, molecular weights, chemical activities, development stages, and research institutions. Its primary advantage lies in rapid retrieval of synthetic routes along with reference sources.

Search conditions support fuzzy queries, with each input condition operating under a logical AND relationship.

Selecting any one condition initiates the search.

2. New Edition of Organic Reactions Named After Individuals Database

http://www.drugfuture.com/Organic_Name_Reactions/index.html

III. Patent Full-Text Download Database  



	 

 

	1. U.S. FDA Drugs Patent Database

http://www.drugfuture.com/fda/drugpatent.aspx

This database contains all valid drug patents recognized and published by the U.S. FDA.

Searching this database provides the following information:

1) By patent number, retrieve details of patented drugs associated with that patent;

2) Search by patent expiration date to find expired U.S. patents and corresponding drug information within any time period;

3) Use the “Drug Online” U.S. patent download feature to directly download full-text patents in PDF/TIF format as a package.

Combined with the U.S. FDA Drug Database launched by Drug Online, this database enables comprehensive access to U.S. market launch information (including registration and approval details) for any drug.  



	 



	2. China Patent Bundle Download

http://www.drugfuture.com/cnpat/cn_patent.asp

Notes:

1) Automatically bundles and downloads the full patent text in one go, eliminating the need to save pages individually.

2) Supports online viewing of the full text.

3) Original patent texts are sourced from the China National Intellectual Property Administration (CNIPA) patent specifications.

4) After selecting a query, the server processes the request and automatically opens the download page; selecting the “PDF Express Download” option enables instant download without waiting.

5) Free download of all Chinese patent specifications published since 1985.

6) Fully supports bundled downloads of both published application specifications and examined granted specifications.

7) Fully supports invention patents, utility model patents, and design patents.

8) Fully supports downloads in Adobe PDF format and TIF image format (zipped into ZIP compressed files).

3. U.S. Patent Bundle Download


http://www.drugfuture.com/uspat/us_patent.asp


Notes:

1) Full texts of all published and granted patent specifications are available for download in PDF and TIF formats.

2) After selecting a query, the server will process it and automatically open the download page upon completion.

3) Original patent texts are sourced from the United States Patent and Trademark Office (USPTO), enabling free download of all published and granted patent documents released by the USPTO from 1790 to present.

4) This site offers multiple download links for bulk U.S. patent downloads; select any one.

5) Fully supports Adobe PDF format and TIF image format (ZIP compressed files). Adobe Acrobat Reader is required to view PDF files.

4. European Patent Bulk Download

http://www.drugfuture.com/eppat/patent.asp

Notes:

1) Original patent texts sourced from the European Patent Office, with full bookmark functionality support.

2) Patent categories can be filtered, e.g., A1, B1, B, C, etc.

3) After selecting a query, the server processes it and automatically opens the download page upon completion.

4) Free access to 3 million patents from worldwide sources held by the EPO, including WO, EP, US, GB, JP, etc.

5) Fully supports Adobe PDF format and TIF image format (ZIP compressed files) downloads. Adobe Acrobat Reader is required to view PDF files.



IV. Drug Registration Information Database  



	 



	





	 



	1. Chinese Marketed Drugs Database

http://www.drugfuture.com/cndrug/

1) This database covers all drugs approved for registration and marketed domestically to date. It provides access to data on all domestically produced and imported drugs approved by the China Food and Drug Administration (CFDA), with weekly updates.

2) Search conditions support fuzzy queries and combined queries, with conditions linked by logical AND. For example, entering “头孢呋辛酯片” or “Cefuroxime Axetil Tablets” in the smart search bar retrieves all registered cefuroxime axetil tablets marketed domestically.

3) Search results include:

① Domestic Drug Registration Database: Approval number, original approval number, drug identification code, identification code annotation, product name, English name, brand name, manufacturer, production address, specification, dosage form, category, approval date, etc.

② Imported Drug Registration Database: Registration certificate number, original registration certificate number, product name, brand name, dosage form, specification, registration certificate remarks, package specification, manufacturer, manufacturer address, manufacturer country, repackaging approval number, issuance date, expiration date, repackaging enterprise name, repackaging enterprise address, repackaging approval date, repackaging approval expiration date, product category, drug code, and drug code remarks.  



	 



	2. U.S. FDA Drugs Database

http://www.drugfuture.com/fda/index.html

1) This database covers all drugs currently marketed or previously marketed in the United States. It provides access to FDA-approved drug registration information, related documents, patent data, market protection, and more, with weekly updates.

2) Search conditions support fuzzy queries and combined queries, with logical AND relationships between conditions. For example, entering “Levofloxacin” in the generic name or active ingredient field will retrieve all levofloxacin products marketed in the U.S.

3) Search results include:

① Brand name, active ingredient, generic name, dosage form, strength, application number, product number, market status, therapeutic equivalence code, approval date, reference drug status, drug category, and applicant.

② FDA-recognized U.S. patents associated with the drug, including patent expiration dates and patent type (compound patent, product patent, use patent). Full patent texts can be downloaded in PDF or TIF format.

③ Market protection status, including market exclusivity type and expiration date.
④ Drug registration approval information, including all historical approval data, approval dates, approval categories, drug labels, summaries, notification letters, etc.

3. Drug Standard Database

http://www.drugfuture.com/standard/index.html

This database compiles domestic and international pharmaceutical standard catalogs and partial full texts, including:

1) National pharmaceutical standards currently include: Chinese Pharmacopoeia 1953 edition, 1963 edition, 1977 Edition, 1985 Edition, 1990 Edition, 1995 Edition (including 1997 and 1998 supplements), 2000 Edition (including 2002 and 2004 supplements), and 2005 Edition (including 2006 and 2009 supplements). Compilation of Quality Standards for Traditional Chinese Medicine Formulations and Raw Materials, Volumes 1-6 of Pharmaceutical Standards, Volumes 1-20 of Traditional Chinese Medicine Formulations, Volumes 1-75 of New Drug Approval Standards, Uyghur Medicine Volume, Mongolian Medicine Volume, Volumes 1-16 of Chemical Drug Local Standards Upgraded to National Standards, Compilation of National Standards for Traditional Chinese Medicine Formulations: Ophthalmology, Otolaryngology, and Dermatology Volume, Compilation of National Standards for Traditional Chinese Medicine Formulations: Surgery and Gynecology Volume, National Compilation of Standards for Chinese Patent Medicines: Internal Medicine - Cardiovascular System Volume, National Compilation of Standards for Chinese Patent Medicines: Internal Medicine - Renal System Volume, National Compilation of Standards for Chinese Patent Medicines: Internal Medicine - Qi, Blood, and Body Fluids Volume, National Compilation of Standards for Chinese Patent Medicines: Internal Medicine - Spleen and Stomach Volume, National Compilation of Standards for Chinese Patent Medicines: Internal Medicine - Liver and Gallbladder Volume, National Compilation of Standards for Chinese Patent Medicines: Internal Medicine - Respiratory System (I) Volume, National Compilation of Standards for Chinese Patent Medicines: Internal Medicine - Respiratory System Volume; Volume (II), National Compilation of Standards for Chinese Patent Medicines: Oral Oncology and Pediatrics Volume, National Compilation of Standards for Chinese Patent Medicines: Meridian, Limb, and Brain System Volume, National Compilation of Standards for Chinese Patent Medicines: Orthopedics Volume, Tibetan Medicine Volume I, Ministry-Issued Antibiotics Volume, Ministry-Issued Chemical Drugs and Preparations. Compilation of Imported Drug Verification Standards, China National Institute for the Control of Pharmaceutical and Biological Products (CNICPB) Imported Drug Verification Standards.

2) Foreign pharmacopoeias currently included:
United States Pharmacopeia USP32-NF27, USP31-NF26;
European Pharmacopoeia 6th Edition;
British Pharmacopoeia BP2009;
Japanese Pharmacopoeia JP15;
International Pharmacopoeia 4th Edition.
Search using English generic names or monograph titles as keywords.

V. Online Pharmacopoeias  



	 



	





	





	 



	1. Chinese Pharmacopoeia 2005 Edition (Preparing to update to the 2010 Edition)

http://www.drugfuture.com/chp2005/chp2005.asp

2. Japanese Pharmacopoeia JP15 Online Edition

http://www.drugfuture.com/Pharmacopoeia/JP15/

3. British Pharmacopoeia Online Edition

http://www.drugfuture.com/Pharmacopoeia/bp2009/

4. United States Pharmacopeia Online Edition

http://www.drugfuture.com/Pharmacopoeia/usp32/